Varaico: Literature-Extracted Genetic Variants

CDT1

171 papers

RefSeq Summary

The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and...

Pfam Domains

CDT1aa 186–349UCSCDNA replication factor CDT1 like

CDT1_Caa 421–516UCSCDNA replication factor Cdt1 C-terminal domain

Gene Aliases

HGNC Name

chromatin licensing and DNA replication factor 1

HGNC Alias Symbols

DUP; RIS2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_030928.4

p.D280N

c.838G>A

Surrounding Variants

1 paper

NM_030928.4

p.A279V

c.836C>T

1 paper

NM_030928.4

p.R290H

c.869G>A

1 paper

NM_030928.4

p.L292insFs

c.874_875ins4

1 paper

NM_030928.4

p.S299_Q300del2

c.895_899del6

1 paper

NM_030928.4

p.V303E

c.908T>A

3 papers

NM_030928.4

p.E278*

c.832G>T

1 paper

NM_030928.4

p.L275P

c.824T>C

2 papers

NM_030928.4

p.T262A

c.784A>G

1 paper

NM_030928.4

p.T257I

c.770C>T

1 paper

NM_030928.4

p.R253fs

c.757_758fs

1 paper

NM_030928.4

p.R250_T262delFs

c.750_784del35

1 paper

NM_030928.4

p.R248L

c.743G>T