Varaico: Literature-Extracted Genetic Variants

CDT1

171 papers

RefSeq Summary

The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and...

Pfam Domains

CDT1aa 186–349UCSCDNA replication factor CDT1 like

CDT1_Caa 421–516UCSCDNA replication factor Cdt1 C-terminal domain

Gene Aliases

HGNC Name

chromatin licensing and DNA replication factor 1

HGNC Alias Symbols

DUP; RIS2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_030928.4

p.S491N

c.1472G>A

Surrounding Variants

1 paper

NM_030928.4

p.G493delFs

c.1477delG

1 paper

NM_030928.4

p.S485insFs

c.1453dupA

1 paper

NM_030928.4

p.V483A

c.1448T>C

5 papers

NM_030928.4

p.E468K

c.1402G>A

1 paper

NM_030928.4

p.F465insFs

c.1393dupT

1 paper

NM_030928.4

p.V464fs

c.1390_1391fs

11 papers

NM_030928.4

p.R462Q

c.1385G>A

1 paper

NM_030928.4

p.E456A

c.1367A>C

5 papers

NM_030928.4

p.R453W

c.1357C>T

1 paper

NM_030928.4

p.E452Q

c.1354G>C

1 paper

NM_030928.4

p.L448_Q449del1

c.1344_1346delGCA

1 paper

NM_030928.4

p.L448_Q449del2

c.1342_1346del6