chromodomain Y-linked 1B

chromodomain protein, Y-linked, 1B

Testis-specific chromodomain protein Y 1

Chromo (CHRromatin Organisation MOdifier) domain

This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

CDY1B

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Name