Varaico: Literature-Extracted Genetic Variants

CERK

70 papers

RefSeq Summary

CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis,...

Pfam Domains

PH_CERKaa 10–119UCSCCeramide kinase PH domain

DAGK_cataa 132–274UCSCDiacylglycerol kinase catalytic domain

CERK_Caa 286–536UCSCCeramide kinase C-terminal domain

Gene Aliases

HGNC Name

ceramide kinase

HGNC Alias Symbols

hCERK; FLJ23239; dA59H18.3; DKFZp434E0211; FLJ21430; KIAA1646; LK4; dA59H18.2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_022766.6

p.P27A

c.79C>G

Surrounding Variants

1 paper

NM_022766.6

p.E26K

c.76G>A

1 paper

NM_022766.6

p.R29G

c.85C>G

1 paper

NM_022766.6

p.C21Y

c.62G>A

1 paper

NM_022766.6

p.R36R

c.106C>A

1 paper

NM_022766.6

p.P38T

c.112C>A

1 paper

NM_022766.6

p.Q11Q

c.33A>G

1 paper

NM_022766.6

p.P9A

c.25C>G

1 paper

NM_022766.6

p.E8A

c.23A>C

2 papers

NM_022766.6

p.G2A

c.5G>C