Varaico: Literature-Extracted Genetic Variants

Gene:CFL1
Variant:p.V64D

CFL1

149 papers

RefSeq Summary

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganizatio...

Pfam Domains

Cofilin_ADFaa 4–153UCSCCofilin/tropomyosin-type actin-binding protein

Gene Aliases

HGNC Name

cofilin 1

HGNC Previous Name

cofilin 1 (non-muscle)

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005507.3
p.V64D
c.191T>A
Surrounding Variants
1 paper
NM_005507.3
p.V64I
c.190G>A
2 papers
NM_005507.3
p.D66D
c.198C>T
1 paper
NM_005507.3
p.G61G
c.183C>T
1 paper
NM_005507.3
p.G61S
c.181G>A
1 paper
NM_005507.3
p.Y68C
c.203A>G
2 papers
NM_005507.3
p.K73R
c.218A>G
1 paper
NM_005507.3
p.K53R
c.158A>G
1 paper
NM_005507.3
p.D77A
c.230A>C
1 paper
NM_005507.3
p.K78R
c.233A>G
1 paper
NM_005507.3
p.E50A
c.149A>C
1 paper
NM_005507.3
p.E50K
c.148G>A
1 paper
NM_005507.3
p.D79Y
c.235G>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."