Varaico: Literature-Extracted Genetic Variants

Gene:CFL1
Variant:p.K33E

CFL1

149 papers

RefSeq Summary

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganizatio...

Pfam Domains

Cofilin_ADFaa 4–153UCSCCofilin/tropomyosin-type actin-binding protein

Gene Aliases

HGNC Name

cofilin 1

HGNC Previous Name

cofilin 1 (non-muscle)

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005507.3
p.K33E
c.97A>G
Surrounding Variants
2 papers
NM_005507.3
p.K33R
c.98A>G
2 papers
NM_005507.3
p.K34R
c.101A>G
1 paper
NM_005507.3
p.K31R
c.92A>G
1 paper
NM_005507.3
p.K30R
c.89A>G
1 paper
NM_005507.3
p.C39S
c.115T>A
2 papers
NM_005507.3
p.C39F
c.116G>T
1 paper
NM_005507.3
p.C39S
c.116G>C
1 paper
NM_005507.3
p.V20_P26insFs
c.59_77dup19
1 paper
NM_005507.3
p.P26fs
c.76_77fs
2 papers
NM_005507.3
p.P26Q
c.77C>A
1 paper
NM_005507.3
p.P26A
c.76C>G
1 paper
NM_005507.3
p.T25T
c.75G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."