Varaico: Literature-Extracted Genetic Variants

CHAF1A

161 papers

RefSeq Summary

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman e...

Pfam Domains

CAF1-p150_Naa 1–226UCSCCAF1 complex subunit p150, region binding to PCNA

CAF1A_acidicaa 326–478UCSCChromatin assembly factor 1 complex p150 subunit, acidic region

CAF1A_dimerizaa 558–632UCSCChromatin assembly factor 1 subunit A dimerization domain

CAF1-p150_C2aa 665–954UCSCCAF1 complex subunit p150, region binding to CAF1-p60 at C-term

Gene Aliases

HGNC Name

chromatin assembly factor 1 subunit A

HGNC Alias Symbols

CAF1P150; CAF1B; CAF-1; CAF1; P150; MGC71229

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005483.3

p.R105S

c.315A>T

Surrounding Variants

1 paper

NM_005483.3

p.R105fs

c.313_314fs

1 paper

NM_005483.3

p.L102S

c.305T>C

1 paper

NM_005483.3

p.K95N

c.285G>C

1 paper

NM_005483.3

p.K95N

c.285G>T

1 paper

NM_005483.3

p.D118A

c.353A>C

1 paper

NM_005483.3

p.T120A

c.358A>G

1 paper

NM_005483.3

p.E121*

c.361G>T

1 paper

NM_005483.3

p.D122Y

c.364G>T

1 paper

NM_005483.3

p.N124delFs

c.372delT

1 paper

NM_005483.3

p.Q126H

c.378G>C

1 paper

NM_005483.3

p.G82insFs

c.245_246insA

1 paper

NM_005483.3

p.K135E

c.403A>G