Varaico: Literature-Extracted Genetic Variants

CHAF1A

161 papers

RefSeq Summary

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman e...

Pfam Domains

CAF1-p150_Naa 1–226UCSCCAF1 complex subunit p150, region binding to PCNA

CAF1A_acidicaa 326–478UCSCChromatin assembly factor 1 complex p150 subunit, acidic region

CAF1A_dimerizaa 558–632UCSCChromatin assembly factor 1 subunit A dimerization domain

CAF1-p150_C2aa 665–954UCSCCAF1 complex subunit p150, region binding to CAF1-p60 at C-term

Gene Aliases

HGNC Name

chromatin assembly factor 1 subunit A

HGNC Alias Symbols

CAF1P150; CAF1B; CAF-1; CAF1; P150; MGC71229

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005483.3

p.E385A

c.1154A>C

Surrounding Variants

1 paper

NM_005483.3

p.R387W

c.1159C>T

1 paper

NM_005483.3

p.R390insFs

c.1168_1169insC

1 paper

NM_005483.3

p.K392K

c.1176G>A

1 paper

NM_005483.3

p.A398A

c.1194G>A

1 paper

NM_005483.3

p.K372del1

c.1114_1116delAAG

1 paper

NM_005483.3

p.R366L

c.1097G>T

1 paper

NM_005483.3

p.R407L

c.1220G>T

1 paper

NM_005483.3

p.R343H

c.1028G>A

1 paper

NM_005483.3

p.R343fs

c.1027_1028fs

1 paper

NM_005483.3

p.R343delFs

c.1028delG

1 paper

NM_005483.3

p.R339_D340Splc

c.1018-2A>G

1 paper

NM_005483.3

p.E421K

c.1261G>A