Varaico: Literature-Extracted Genetic Variants

CHAF1A

161 papers

RefSeq Summary

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman e...

Pfam Domains

CAF1-p150_Naa 1–226UCSCCAF1 complex subunit p150, region binding to PCNA

CAF1A_acidicaa 326–478UCSCChromatin assembly factor 1 complex p150 subunit, acidic region

CAF1A_dimerizaa 558–632UCSCChromatin assembly factor 1 subunit A dimerization domain

CAF1-p150_C2aa 665–954UCSCCAF1 complex subunit p150, region binding to CAF1-p60 at C-term

Gene Aliases

HGNC Name

chromatin assembly factor 1 subunit A

HGNC Alias Symbols

CAF1P150; CAF1B; CAF-1; CAF1; P150; MGC71229

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_005483.3

p.R567Q

c.1700G>A

Surrounding Variants

1 paper

NM_005483.3

p.C563*

c.1689T>A

1 paper

NM_005483.3

p.C563delFs

c.1687_1688delTG

1 paper

NM_005483.3

p.K577E

c.1729A>G

1 paper

NM_005483.3

p.T578M

c.1733C>T

1 paper

NM_005483.3

p.K553E

c.1657A>G

1 paper

NM_005483.3

p.R582C

c.1744C>T

1 paper

NM_005483.3

p.A583T

c.1747G>A

1 paper

NM_005483.3

p.A583V

c.1748C>T

1 paper

NM_005483.3

p.R584*

c.1750C>T

2 papers

NM_005483.3

p.G547S

c.1639G>A

1 paper

NM_005483.3

p.G545G

c.1635C>T

1 paper

NM_005483.3

p.G545fs

c.1633_1634fs