Varaico: Literature-Extracted Genetic Variants

CHAF1A

161 papers

RefSeq Summary

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman e...

Pfam Domains

CAF1-p150_Naa 1–226UCSCCAF1 complex subunit p150, region binding to PCNA

CAF1A_acidicaa 326–478UCSCChromatin assembly factor 1 complex p150 subunit, acidic region

CAF1A_dimerizaa 558–632UCSCChromatin assembly factor 1 subunit A dimerization domain

CAF1-p150_C2aa 665–954UCSCCAF1 complex subunit p150, region binding to CAF1-p60 at C-term

Gene Aliases

HGNC Name

chromatin assembly factor 1 subunit A

HGNC Alias Symbols

CAF1P150; CAF1B; CAF-1; CAF1; P150; MGC71229

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005483.3

p.R731T

c.2192G>C

Surrounding Variants

1 paper

NM_005483.3

p.E733V

c.2198A>T

2 papers

NM_005483.3

p.S726F

c.2177C>T

1 paper

NM_005483.3

p.I735Splc

c.2203+25C>T

1 paper

NM_005483.3

p.C710R

c.2128T>C

1 paper

NM_005483.3

p.A697E

c.2090C>A

1 paper

NM_005483.3

p.A691V

c.2072C>T

1 paper

NM_005483.3

p.W690*

c.2070G>A

1 paper

NM_005483.3

p.W690*

c.2069G>A

1 paper

NM_005483.3

p.C688S

c.2063G>C

1 paper

NM_005483.3

p.C688S

c.2062T>A

1 paper

NM_005483.3

p.V684M

c.2050G>A

1 paper

NM_005483.3

p.Q682H

c.2046A>C