coiled-coil-helix-coiled-coil-helix domain containing 3

FLJ20420

MINOS3

PPP1R22

Mic19

MICOS19

mitochondrial inner membrane organizing system 3

protein phosphatase 1, regulatory subunit 22

mitochondrial contact site and cristae organizing system subunit 19

MICOS complex subunit MIC19

Coiled-coil-helix-coiled-coil-helix domain-containing protein 3

The protein encoded by this gene is an inner mitochondrial membrane scaffold protein. Absence of the encoded protein affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. This protein is part of the mitochondrial contact site and cristae organizing system (MICOS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015].

Varaico: Literature-Extracted Genetic Variants

CHCHD3

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols