chloride intracellular channel 5

DFNB102

Chloride intracellular channel protein 5

Glutaredoxin-like oxidoreductase CLIC5

Glutathione S-transferase, C-terminal domain

This gene encodes a member of the chloride intracellular channel (CLIC) family of chloride ion channels. The encoded protein associates with actin-based cytoskeletal structures and may play a role in multiple processes including hair cell stereocilia formation, myoblast proliferation and glomerular podocyte and endothelial cell maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].

Varaico: Literature-Extracted Genetic Variants

CLIC5

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbol