Varaico: Literature-Extracted Genetic Variants

Gene:CLOCK
Variant:p.G673R

CLOCK

153 papers

RefSeq Summary

The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA bi...

Pfam Domains

HLHaa 35–85UCSCHelix-loop-helix DNA-binding domain
PASaa 109–189UCSCPAS fold
PAS_11aa 273–380UCSCPAS domain

Gene Aliases

HGNC Name

clock circadian regulator

HGNC Alias Symbols

KIAA0334; KAT13D; bHLHe8

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004898.4
p.G673R
c.2017G>A
Surrounding Variants
1 paper
NM_004898.4
p.G673R
c.2017G>C
1 paper
NM_004898.4
p.S668Y
c.2003C>A
1 paper
NM_004898.4
p.T664A
c.1990A>G
1 paper
NM_004898.4
p.Y662C
c.1985A>G
1 paper
NM_004898.4
p.S655G
c.1963A>G
1 paper
NM_004898.4
p.P650S
c.1948C>T
1 paper
NM_004898.4
p.R699K
c.2096G>A
1 paper
NM_004898.4
p.I701T
c.2102T>C
1 paper
NM_004898.4
p.V639G
c.1916T>G
1 paper
NM_004898.4
p.S632T
c.1894T>A
1 paper
NM_004898.4
p.N588N
c.1764T>C
1 paper
NM_004898.4
p.S582_S583delFs
c.1744_1747del4
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."