CKLF like MARVEL transmembrane domain containing 8

CKLFSF8

chemokine-like factor super family 8

chemokine-like factor superfamily 8

CKLF-like MARVEL transmembrane domain containing 8

CKLF-like MARVEL transmembrane domain-containing protein 8

Chemokine-like factor superfamily member 8

This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016].

Varaico: Literature-Extracted Genetic Variants

CMTM8

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol