CCR4-NOT transcription complex subunit 2

NOT2

CDC36

NOT2H

CCR4-NOT transcription complex, subunit 2

CC chemokine receptor 4-negative regulator of transcription 2

CCR4-associated factor 2

This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010].

Varaico: Literature-Extracted Genetic Variants

CNOT2

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol