component of oligomeric golgi complex 2

LDLC

low density lipoprotein receptor defect C complementing

Conserved oligomeric Golgi complex subunit 2

Component of oligomeric Golgi complex 2

Low density lipoprotein receptor defect C-complementing protein

COG complex subunit 2

This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009].

Varaico: Literature-Extracted Genetic Variants

COG2

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol