Varaico: Literature-Extracted Genetic Variants

Gene:COMT
Variant:p.L22M

COMT

2,857 papers

RefSeq Summary

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-met...

Pfam Domains

Methyltransf_3aa 67–228UCSCO-methyltransferase

Gene Aliases

HGNC Name

catechol-O-methyltransferase

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000754.4
p.L22M
c.64C>A
Surrounding Variants
1 paper
NM_000754.4
p.L22V
c.64C>G
1 paper
NM_000754.4
p.L22L
c.64C>T
1 paper
NM_000754.4
p.V21V
c.63G>C
1 paper
NM_000754.4
p.L22Q
c.65T>A
1 paper
NM_000754.4
p.L22P
c.65T>C
1 paper
NM_000754.4
p.L22R
c.65T>G
1 paper
NM_000754.4
p.V21E
c.62T>A
1 paper
NM_000754.4
p.V21A
c.62T>C
1 paper
NM_000754.4
p.V21G
c.62T>G
1 paper
NM_000754.4
p.L23M
c.67C>A
1 paper
NM_000754.4
p.L23V
c.67C>G
1 paper
NM_000754.4
p.V21M
c.61G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."