Varaico: Literature-Extracted Genetic Variants

Gene:COMT
Variant:p.L25H

COMT

2,857 papers

RefSeq Summary

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-met...

Pfam Domains

Methyltransf_3aa 67–228UCSCO-methyltransferase

Gene Aliases

HGNC Name

catechol-O-methyltransferase

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000754.4
p.L25H
c.74T>A
Surrounding Variants
1 paper
NM_000754.4
p.L25P
c.74T>C
1 paper
NM_000754.4
p.L25R
c.74T>G
1 paper
NM_000754.4
p.L25I
c.73C>A
1 paper
NM_000754.4
p.L25V
c.73C>G
1 paper
NM_000754.4
p.L25F
c.73C>T
1 paper
NM_000754.4
p.L26M
c.76C>A
2 papers
NM_000754.4
p.L26V
c.76C>G
1 paper
NM_000754.4
p.L24Q
c.71T>A
1 paper
NM_000754.4
p.L26Q
c.77T>A
2 papers
NM_000754.4
p.L26P
c.77T>C
1 paper
NM_000754.4
p.L24P
c.71T>C
1 paper
NM_000754.4
p.L24R
c.71T>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."