Varaico: Literature-Extracted Genetic Variants

Gene:COMT
Variant:p.N61K

COMT

2,857 papers

RefSeq Summary

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-met...

Pfam Domains

Methyltransf_3aa 67–228UCSCO-methyltransferase

Gene Aliases

HGNC Name

catechol-O-methyltransferase

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000754.4
p.N61K
c.183C>G
Surrounding Variants
1 paper
NM_007310.3
p.N11K
c.33C>A
2 papers
NM_000754.4
p.H62Y
c.184C>T
1 paper
NM_000754.4
p.H62P
c.185A>C
1 paper
NM_000754.4
p.H62R
c.185A>G
1 paper
NM_000754.4
p.H62L
c.185A>T
6 papers
NM_000754.4
p.H62Q
c.186C>G
22 papers
NM_000754.4
p.H62H
c.186C>T
NM_007310.3
p.H12H
c.36C>T
2 papers
NM_000754.4
p.V63L
c.187G>C
1 paper
NM_000754.4
p.V63L
c.187G>T
1 paper
NM_000754.4
p.L60P
c.179T>C
3 papers
NM_000754.4
p.L60L
c.178C>T
1 paper
NM_000754.4
p.V63E
c.188T>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."