Varaico: Literature-Extracted Genetic Variants

Gene:COMT
Variant:p.V158L

COMT

2,857 papers

RefSeq Summary

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-met...

Pfam Domains

Methyltransf_3aa 67–228UCSCO-methyltransferase

Gene Aliases

HGNC Name

catechol-O-methyltransferase

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000754.4
p.V158L
c.472G>C
Surrounding Variants
2415 papers
NM_000754.4
p.V158M
c.472G>A
NM_007310.3
p.V108M
c.322G>A
1 paper
NM_000754.4
p.V158L
c.472G>T
3 papers
NM_000754.4
p.V158G
c.473T>G
1 paper
NM_000754.4
p.K159del1
c.475_476delAAG
1 paper
NM_000754.4
p.K159E
c.475A>G
2 papers
NM_000754.4
p.A156T
c.466G>A
1 paper
NM_000754.4
p.F155L
c.465C>A
1 paper
NM_000754.4
p.D160D
c.480C>T
5 papers
NM_000754.4
p.D154N
c.460G>A
3 papers
NM_000754.4
p.V153M
c.457G>A
2 papers
NM_000754.4
p.M152T
c.455T>C
1 paper
NM_000754.4
p.M152L
c.454A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."