Varaico: Literature-Extracted Genetic Variants

COPS3

25 papers

RefSeq Summary

The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site ...

Pfam Domains

COP9_hel_rptaa 18–249UCSCCOP9 signalosome complex subunit 3, N-terminal helical repeats

PCIaa 279–362UCSCPCI domain

CSN3-like_Caa 369–396UCSCCOP9 signalosome complex subunit 3-like, C-terminal helix

Gene Aliases

HGNC Name

COP9 signalosome subunit 3

HGNC Alias Symbol

SGN3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003653.4

p.D43E

c.129C>A

Surrounding Variants

1 paper

NM_003653.4

p.D43E

c.129C>G

1 paper

NM_003653.4

p.V51A

c.152T>C

1 paper

NM_003653.4

p.A2A

c.6G>A

1 paper

NM_003653.4

p.S70T

c.209G>C

1 paper

NM_003653.4

p.S86S

c.258C>T

1 paper

NM_003653.4

p.C88R

c.262T>C