Varaico: Literature-Extracted Genetic Variants

Gene:CPA1
Variant:p.R108W

CPA1

133 papers

RefSeq Summary

This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino ac...

Pfam Domains

Propep_M14aa 26–100UCSCCarboxypeptidase activation peptide
Peptidase_M14aa 128–406UCSCZinc carboxypeptidase

Gene Aliases

HGNC Name

carboxypeptidase A1

HGNC Previous Name

carboxypeptidase A1 (pancreatic)

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001868.4
p.R108W
c.322C>T
Surrounding Variants
1 paper
NM_001868.4
p.F107L
c.321C>A
1 paper
NM_001868.4
p.F107L
c.321C>G
1 paper
NM_001868.4
p.R108Q
c.323G>A
1 paper
NM_001868.4
p.F107L
c.319T>C
1 paper
NM_001868.4
p.F105L
c.315C>A
1 paper
NM_001868.4
p.F105L
c.315C>G
1 paper
NM_001868.4
p.F105L
c.313T>C
1 paper
NM_001868.4
p.R112C
c.334C>T
2 papers
NM_001868.4
p.E100K
c.298G>A
1 paper
NM_001868.4
p.E99Q
c.295G>C
1 paper
NM_001868.4
p.Y119C
c.356A>G
2 papers
NM_001868.4
p.Y119*
c.357C>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."