Varaico: Literature-Extracted Genetic Variants

Gene:CPA1
Variant:p.R382W

CPA1

133 papers

RefSeq Summary

This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino ac...

Pfam Domains

Propep_M14aa 26–100UCSCCarboxypeptidase activation peptide
Peptidase_M14aa 128–406UCSCZinc carboxypeptidase

Gene Aliases

HGNC Name

carboxypeptidase A1

HGNC Previous Name

carboxypeptidase A1 (pancreatic)

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
7 papers
NM_001868.4
p.R382W
c.1144C>T
Surrounding Variants
1 paper
NM_001868.4
p.R382Q
c.1145G>A
2 papers
NM_001868.4
p.E380K
c.1138G>A
2 papers
NM_001868.4
p.R386C
c.1156C>T
2 papers
NM_001868.4
p.R386H
c.1157G>A
1 paper
NM_001868.4
p.Y387insFs
c.1160_1161insT
1 paper
NM_001868.4
p.G388S
c.1162G>A
2 papers
NM_001868.4
p.S376P
c.1126T>C
7 papers
NM_001868.4
p.K374E
c.1120A>G
1 paper
NM_001868.4
p.G372D
c.1115G>A
1 paper
NM_001868.4
p.Y369Y
c.1107C>T
1 paper
NM_001868.4
p.I396V
c.1186A>G
1 paper
NM_001868.4
p.D366H
c.1096G>C
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