carboxypeptidase N subunit 1

carboxypeptidase N, polypeptide 1, 50kD

carboxypeptidase N, polypeptide 1

anaphylatoxin inactivator

arginine carboxypeptidase

carboxypeptidase K

kininase I

lysine carboxypeptidase

Carboxypeptidase N catalytic chain

Anaphylatoxin inactivator

Arginine carboxypeptidase

Carboxypeptidase N polypeptide 1

Carboxypeptidase N small subunit

Kininase-1

Lysine carboxypeptidase

Plasma carboxypeptidase B

Serum carboxypeptidase N

SCPN

Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

CPN1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Names