Varaico: Literature-Extracted Genetic Variants

CRBN

173 papers

RefSeq Summary

This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and ...

Pfam Domains

LON_substr_bdgaa 80–317UCSCATP-dependent protease La (LON) substrate-binding domain

Yippee-Mis18aa 319–437UCSCYippee zinc-binding/DNA-binding /Mis18, centromere assembly

Gene Aliases

HGNC Name

cereblon

HGNC Previous Symbol

MRT2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016302.4

p.T138delFs

c.414delT

Surrounding Variants

1 paper

NM_016302.4

p.A139fs

c.415_416fs

1 paper

NM_016302.4

p.E140fs

c.418_419fs

1 paper

NM_016302.4

p.E140_I141delFs

c.420_421delTC

1 paper

NM_016302.4

p.A143V

c.428C>T

1 paper

NM_016302.4

p.Y144C

c.431A>G

1 paper

NM_016302.4

p.E132K

c.394G>A

1 paper

NM_016302.4

p.E130G

c.389A>G

1 paper

NM_016302.4

p.V128I

c.382G>A

2 papers

NM_016302.4

p.N127S

c.380A>G

1 paper

NM_016302.4

p.G151*

c.451G>T

1 paper

NM_016302.4

p.G151V

c.452G>T

1 paper

NM_016302.4

p.G151A

c.452G>C