Varaico: Literature-Extracted Genetic Variants

CRBN

173 papers

RefSeq Summary

This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and ...

Pfam Domains

LON_substr_bdgaa 80–317UCSCATP-dependent protease La (LON) substrate-binding domain

Yippee-Mis18aa 319–437UCSCYippee zinc-binding/DNA-binding /Mis18, centromere assembly

Gene Aliases

HGNC Name

cereblon

HGNC Previous Symbol

MRT2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016302.4

p.D76N

c.226G>A

Surrounding Variants

1 paper

NM_016302.4

p.S77T

c.230G>C

1 paper

NM_016302.4

p.D74H

c.220G>C

1 paper

NM_016302.4

p.H73H

c.219C>T

1 paper

NM_016302.4

p.H73Q

c.219C>G

1 paper

NM_016302.4

p.H73Q

c.219C>A

1 paper

NM_016302.4

p.Q79E

c.235C>G

1 paper

NM_016302.4

p.Q79fs

c.235_236fs

1 paper

NM_016302.4

p.V83L

c.247G>C

1 paper

NM_016302.4

p.H68_G69ins4

c.202_206ins12

2 papers

NM_016302.4

p.P85S

c.253C>T

1 paper

NM_016302.4

p.L60P

c.179T>C

1 paper

NM_016302.4

p.Y59H

c.175T>C