Varaico: Literature-Extracted Genetic Variants

CRK

889 papers

RefSeq Summary

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is i...

Pfam Domains

SH2aa 13–104UCSCSH2 domain

SH3_1aa 138–184UCSCSH3 domain

SH3_2aa 239–294UCSCVariant SH3 domain

Gene Aliases

HGNC Name

CRK proto-oncogene, adaptor protein

HGNC Previous Name

v-crk avian sarcoma virus CT10 oncogene homolog

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016823.4

p.A257V

c.770C>T

Surrounding Variants

1 paper

NM_016823.4

p.L258S

c.773T>C

1 paper

NM_016823.4

p.A255A

c.765C>G

1 paper

NM_016823.4

p.E259_V260Splc

c.777+1G>A

1 paper

NM_016823.4

p.A250A

c.750C>G

1 paper

NM_016823.4

p.P248P

c.744C>A

1 paper

NM_016823.4

p.P248S

c.742C>T

1 paper

NM_016823.4

p.V247F

c.739G>T

1 paper

NM_016823.4

p.R246_V247insFs

c.738_739insTG

1 paper

NM_016823.4

p.V242V

c.726T>A

1 paper

NM_016823.4

p.I238I

c.714A>T

1 paper

NM_016823.4

p.G236R

c.706G>A

1 paper

NM_016823.4

p.V226delFs

c.676delC