Varaico: Literature-Extracted Genetic Variants

CRK

889 papers

RefSeq Summary

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is i...

Pfam Domains

SH2aa 13–104UCSCSH2 domain

SH3_1aa 138–184UCSCSH3 domain

SH3_2aa 239–294UCSCVariant SH3 domain

Gene Aliases

HGNC Name

CRK proto-oncogene, adaptor protein

HGNC Previous Name

v-crk avian sarcoma virus CT10 oncogene homolog

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016823.4

p.R160K

c.479G>A

Surrounding Variants

1 paper

NM_016823.4

p.I161L

c.481A>C

1 paper

NM_016823.4

p.D157_R160del4

c.469_479del12

1 paper

NM_016823.4

p.R162P

c.485G>C

1 paper

NM_016823.4

p.R162Q

c.485G>A

1 paper

NM_016823.4

p.D163V

c.488A>T

1 paper

NM_016823.4

p.D163A

c.488A>C

3 papers

NM_016823.4

p.D157N

c.469G>A

1 paper

NM_016823.4

p.D163D

c.489C>T

1 paper

NM_016823.4

p.E167V

c.500A>T

1 paper

NM_016823.4

p.E167delFs

c.501delC

1 paper

NM_016823.4

p.L151F

c.451C>T

1 paper

NM_016823.4

p.L151I

c.451C>A