Varaico: Literature-Extracted Genetic Variants

CRK

889 papers

RefSeq Summary

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is i...

Pfam Domains

SH2aa 13–104UCSCSH2 domain

SH3_1aa 138–184UCSCSH3 domain

SH3_2aa 239–294UCSCVariant SH3 domain

Gene Aliases

HGNC Name

CRK proto-oncogene, adaptor protein

HGNC Previous Name

v-crk avian sarcoma virus CT10 oncogene homolog

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016823.4

p.Y136C

c.407A>G

Surrounding Variants

1 paper

NM_016823.4

p.Y136F

c.407A>T

1 paper

NM_016823.4

p.E135G

c.404A>G

1 paper

NM_016823.4

p.R138L

c.413G>T

1 paper

NM_016823.4

p.A134V

c.401C>T

1 paper

NM_016823.4

p.A134delFs

c.400delC

1 paper

NM_016823.4

p.A134T

c.400G>A

1 paper

NM_016823.4

p.E133A

c.398A>C

1 paper

NM_016823.4

p.E132E

c.396G>A

1 paper

NM_016823.4

p.L140I

c.418C>A

1 paper

NM_016823.4

p.Q131K

c.391C>A

1 paper

NM_016823.4

p.F143L

c.427T>C

1 paper

NM_016823.4

p.L129L

c.387C>T