Varaico: Literature-Extracted Genetic Variants

CRK

889 papers

RefSeq Summary

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is i...

Pfam Domains

SH2aa 13–104UCSCSH2 domain

SH3_1aa 138–184UCSCSH3 domain

SH3_2aa 239–294UCSCVariant SH3 domain

Gene Aliases

HGNC Name

CRK proto-oncogene, adaptor protein

HGNC Previous Name

v-crk avian sarcoma virus CT10 oncogene homolog

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016823.4

p.E116Q

c.346G>C

Surrounding Variants

1 paper

NM_016823.4

p.E116K

c.346G>A

1 paper

NM_016823.4

p.E116G

c.347A>G

1 paper

NM_016823.4

p.I115M

c.345A>G

1 paper

NM_016823.4

p.P117S

c.349C>T

1 paper

NM_016823.4

p.L114M

c.340T>A

1 paper

NM_016823.4

p.V118V

c.354T>G

1 paper

NM_016823.4

p.S119A

c.355T>G

2 papers

NM_016823.4

p.R120G

c.358A>G

1 paper

NM_016823.4

p.R122K

c.365G>A

1 paper

NM_016823.4

p.L109W

c.326T>G

1 paper

NM_016823.4

p.Q123H

c.369G>C

1 paper

NM_016823.4

p.Y108C

c.323A>G