Varaico: Literature-Extracted Genetic Variants

CRK

889 papers

RefSeq Summary

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is i...

Pfam Domains

SH2aa 13–104UCSCSH2 domain

SH3_1aa 138–184UCSCSH3 domain

SH3_2aa 239–294UCSCVariant SH3 domain

Gene Aliases

HGNC Name

CRK proto-oncogene, adaptor protein

HGNC Previous Name

v-crk avian sarcoma virus CT10 oncogene homolog

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016823.4

p.N63K

c.189C>G

Surrounding Variants

2 papers

NM_016823.4

p.N63K

c.189C>A

1 paper

NM_016823.4

p.R56_I62ins2

c.168_185dup18

1 paper

NM_016823.4

p.I62delFs

c.185_186delGA

1 paper

NM_016823.4

p.S64_S65insFs

c.192_193insG

1 paper

NM_016823.4

p.S65N

c.194G>A

1 paper

NM_016823.4

p.I61N

c.182T>A

1 paper

NM_016823.4

p.R68S

c.202C>A

1 paper

NM_016823.4

p.H59L

c.176A>T

1 paper

NM_016823.4

p.R68P

c.203G>C

1 paper

NM_016823.4

p.P69A

c.205C>G

1 paper

NM_016823.4

p.S58C

c.173C>G

2 papers

NM_016823.4

p.S58A

c.172T>G