Varaico: Literature-Extracted Genetic Variants

CRLF2

226 papers

RefSeq Summary

This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encod...

Pfam Domains

TSLPR_D1aa 32–111UCSCCytokine receptor-like factor 2, domain 1

CRLF2-like_D2aa 119–212UCSCCytokine receptor-like factor 2-like, D2 domain

Gene Aliases

HGNC Name

cytokine receptor like factor 2

HGNC Alias Symbols

CRL2; TSLPR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_022148.4

p.E220D

c.660G>C

Surrounding Variants

2 papers

NM_022148.4

p.E220D

c.660G>T

1 paper

NM_022148.4

p.E220*

c.658G>T

1 paper

NM_022148.4

p.T223M

c.668C>T

2 papers

NM_022148.4

p.P224L

c.671C>T

1 paper

NM_022148.4

p.P225R

c.674C>G

1 paper

NM_022148.4

p.S230C

c.689C>G

63 papers

NM_022148.4

p.F232C

c.695T>G

1 paper

NM_022148.4

p.F232Y

c.695T>A

1 paper

NM_022148.4

p.L234ins1

c.700_701insGCC

1 paper

NM_022148.4

p.L234F

c.702A>T

1 paper

NM_022148.4

p.L234F

c.702A>C

2 papers

NM_022148.4

p.S236F

c.707C>T