cartilage acidic protein 1

FLJ10320

CEP-68

ASPIC1

Cartilage acidic protein 1

68 kDa chondrocyte-expressed protein

ASPIC

This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011].

Varaico: Literature-Extracted Genetic Variants

CRTAC1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols