Varaico: Literature-Extracted Genetic Variants

Gene:CRY1
Variant:p.Y432F

CRY1

102 papers

RefSeq Summary

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK...

Pfam Domains

DNA_photolyaseaa 5–169UCSCDNA photolyase
FAD_binding_7aa 285–486UCSCFAD binding domain of DNA photolyase

Gene Aliases

HGNC Name

cryptochrome circadian regulator 1

HGNC Previous Symbol

PHLL1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004075.5
p.Y432F
c.1295A>T
Surrounding Variants
1 paper
NM_004075.5
p.Y432D
c.1294T>G
3 papers
NM_004075.5
p.R431H
c.1292G>A
1 paper
NM_004075.5
p.R431C
c.1291C>T
1 paper
NM_004075.5
p.L436R
c.1307T>G
1 paper
NM_004075.5
p.Y445C
c.1334A>G
1 paper
NM_004075.5
p.P447L
c.1340C>T
1 paper
NM_004075.5
p.I454M
c.1362C>G
1 paper
NM_004075.5
p.Q455*
c.1363C>T
1 paper
NM_004075.5
p.V464I
c.1390G>A
1 paper
NM_004075.5
p.P467H
c.1400C>A
1 paper
NM_004075.5
p.Y488D
c.1462T>G
1 paper
NM_004075.5
p.N425S
c.1274A>G
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