Varaico: Literature-Extracted Genetic Variants

CRY2

83 papers

RefSeq Summary

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK...

Pfam Domains

DNA_photolyaseaa 24–187UCSCDNA photolyase

FAD_binding_7aa 304–505UCSCFAD binding domain of DNA photolyase

Gene Aliases

HGNC Name

cryptochrome circadian regulator 2

HGNC Previous Names

cryptochrome 2 (photolyase-like); cryptochrome circadian clock 2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_021117.5

p.K87I

c.260A>T

Surrounding Variants

1 paper

NM_021117.5

p.K87*

c.259A>T

1 paper

NM_021117.5

p.N89N

c.267C>T

1 paper

NM_021117.5

p.R96W

c.286C>T

1 paper

NM_021117.5

p.P123L

c.368C>T

1 paper

NM_021117.5

p.G162W

c.484G>T

1 paper

NM_021117.5

p.P165Q

c.494C>A

1 paper

NM_021117.5

p.R171C

c.511C>T

1 paper

NM_021117.5

p.R178C

c.532C>T

1 paper

NM_021117.5

p.L188_V189delFs

c.562_566del5

1 paper

NM_021117.5

p.L188fs

c.562_563fs

1 paper

NM_021117.5

p.Q192*

c.574C>T

1 paper

NM_021117.5

p.R246W

c.736C>T