Varaico: Literature-Extracted Genetic Variants

CSK

204 papers

RefSeq Summary

The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the prot...

Pfam Domains

SH3_1aa 15–62UCSCSH3 domain

SH2aa 82–156UCSCSH2 domain

PK_Tyr_Ser-Thraa 195–440UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

C-terminal Src kinase

HGNC Previous Names

c-src tyrosine kinase; CSK, non-receptor tyrosine kinase

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004383.3

p.A339V

c.1016C>T

Surrounding Variants

1 paper

NM_004383.3

p.S341N

c.1022G>A

1 paper

NM_004383.3

p.Q343K

c.1027C>A

1 paper

NM_004383.3

p.D332G

c.995A>G

1 paper

NM_004383.3

p.D332N

c.994G>A

1 paper

NM_004383.3

p.K329N

c.987G>C

1 paper

NM_004383.3

p.K329N

c.987G>T

1 paper

NM_004383.3

p.V350I

c.1048G>A

1 paper

NM_004383.3

p.V350insFs

c.1048_1049ins5

1 paper

NM_004383.3

p.N326D

c.976A>G

1 paper

NM_004383.3

p.N319S

c.956A>G

1 paper

NM_004383.3

p.E360*

c.1078G>T

1 paper

NM_004383.3

p.R318H

c.953G>A