Varaico: Literature-Extracted Genetic Variants

Gene:CUL3
Variant:p.S450delFs

CUL3

494 papers

RefSeq Summary

This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core compo...

Pfam Domains

Cullinaa 34–484UCSCCullin alpha solenoid domain
Cullin_ABaa 507–665UCSCCullin alpha+beta domain
Cullin_Nedd8aa 698–760UCSCCullin protein neddylation domain

Gene Aliases

HGNC Name

cullin 3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_003590.5
p.S450delFs
c.1349_1350delAG
Surrounding Variants
1 paper
NM_003590.5
p.E451*
c.1351G>T
1 paper
NM_003590.5
p.E451K
c.1351G>A
1 paper
NM_003590.5
p.S450delFs
c.1349delG
1 paper
NM_003590.5
p.D449_E451delFs
c.1347_1351del5
1 paper
NM_003590.5
p.V446_S450delFs
c.1336_1348del13
1 paper
NM_003590.5
p.K452E
c.1354A>G
3 papers
NM_003590.5
p.N453fs
c.1357_1358fs
1 paper
NM_003590.5
p.N453fs
c.1357_1358fs
3 papers
NM_003590.5
p.N453insFs
c.1358dupA
1 paper
NM_003590.5
p.N453delFs
c.1358delT
1 paper
NM_003590.5
p.M454delFs
c.1360delT
1 paper
NM_003590.5
p.V446delFs
c.1336_1337delAC
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