Varaico: Literature-Extracted Genetic Variants

Gene:CUL3
Variant:p.F419delFs

CUL3

494 papers

RefSeq Summary

This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core compo...

Pfam Domains

Cullinaa 34–484UCSCCullin alpha solenoid domain
Cullin_ABaa 507–665UCSCCullin alpha+beta domain
Cullin_Nedd8aa 698–760UCSCCullin protein neddylation domain

Gene Aliases

HGNC Name

cullin 3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003590.5
p.F419delFs
c.1257delA
Surrounding Variants
1 paper
NM_003590.5
p.M422L
c.1264A>T
1 paper
NM_003590.5
p.M422L
c.1264A>C
1 paper
NM_003590.5
p.M422_Q423insA
c.1264_1268ins3
1 paper
NM_003590.5
p.M416del1
c.1246_1247delCAT
1 paper
NM_003590.5
p.M416delFs
c.1246_1247delAT
1 paper
NM_003590.5
p.E424*
c.1270G>T
2 papers
NM_003590.5
p.E424Q
c.1270G>C
1 paper
NM_003590.5
p.E424K
c.1270G>A
4 papers
NM_003590.5
p.D413delFs
c.1239delA
7 papers
NM_003590.5
p.D413G
c.1238A>G
4 papers
NM_003590.5
p.D413fs
c.1237_1238fs
7 papers
NM_003590.5
p.L412L
c.1236G>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."