Varaico: Literature-Extracted Genetic Variants

Gene:CUL3
Variant:p.D413delFs

CUL3

494 papers

RefSeq Summary

This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core compo...

Pfam Domains

Cullinaa 34–484UCSCCullin alpha solenoid domain
Cullin_ABaa 507–665UCSCCullin alpha+beta domain
Cullin_Nedd8aa 698–760UCSCCullin protein neddylation domain

Gene Aliases

HGNC Name

cullin 3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_003590.5
p.D413delFs
c.1239delA
Surrounding Variants
7 papers
NM_003590.5
p.D413G
c.1238A>G
4 papers
NM_003590.5
p.D413fs
c.1237_1238fs
7 papers
NM_003590.5
p.L412L
c.1236G>A
1 paper
NM_003590.5
p.M416delFs
c.1246_1247delAT
1 paper
NM_003590.5
p.M416del1
c.1246_1247delCAT
2 papers
NM_003590.5
p.T410I
c.1229C>T
1 paper
NM_003590.5
p.V408V
c.1224A>T
3 papers
NM_003590.5
p.V408V
c.1224A>G
1 paper
NM_003590.5
p.V408V
c.1224A>C
1 paper
NM_003590.5
p.V408G
c.1223T>G
1 paper
NM_003590.5
p.V408A
c.1223T>C
1 paper
NM_003590.5
p.V408E
c.1223T>A
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