Varaico: Literature-Extracted Genetic Variants

Gene:CUL3
Variant:p.V408V

CUL3

494 papers

RefSeq Summary

This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core compo...

Pfam Domains

Cullinaa 34–484UCSCCullin alpha solenoid domain
Cullin_ABaa 507–665UCSCCullin alpha+beta domain
Cullin_Nedd8aa 698–760UCSCCullin protein neddylation domain

Gene Aliases

HGNC Name

cullin 3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_003590.5
p.V408V
c.1224A>G
Surrounding Variants
1 paper
NM_003590.5
p.V408V
c.1224A>T
1 paper
NM_003590.5
p.V408V
c.1224A>C
1 paper
NM_003590.5
p.V408G
c.1223T>G
1 paper
NM_003590.5
p.V408A
c.1223T>C
1 paper
NM_003590.5
p.V408E
c.1223T>A
1 paper
NM_003590.5
p.V408L
c.1222G>T
1 paper
NM_003590.5
p.V408L
c.1222G>C
1 paper
NM_003590.5
p.V408I
c.1222G>A
1 paper
NM_003590.5
p.E407D
c.1221A>T
7 papers
NM_003590.5
p.E407E
c.1221A>G
1 paper
NM_003590.5
p.E407D
c.1221A>C
1 paper
NM_003590.5
p.E407V
c.1220A>T
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