Varaico: Literature-Extracted Genetic Variants

Gene:CUL3
Variant:p.G402_L403Splc

CUL3

494 papers

RefSeq Summary

This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core compo...

Pfam Domains

Cullinaa 34–484UCSCCullin alpha solenoid domain
Cullin_ABaa 507–665UCSCCullin alpha+beta domain
Cullin_Nedd8aa 698–760UCSCCullin protein neddylation domain

Gene Aliases

HGNC Name

cullin 3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_003590.5
p.G402_L403Splc
c.1207-3C>T
Surrounding Variants
2 papers
NM_003590.5
p.G402_L403Splc
c.1207-3C>A
2 papers
NM_003590.5
p.G402_L403Splc
c.1207-2A>G
1 paper
NM_003590.5
p.G402_L403Splc
c.1207-2A>C
4 papers
NM_003590.5
p.G402_L403Splc
c.1207-5T>A
11 papers
NM_003590.5
p.G402_L403Splc
c.1207-1G>A
6 papers
NM_003590.5
p.G402_L403Splc
c.1207-6T>G
1 paper
NM_003590.5
p.G402_L403Splc
c.1207-9A>T
1 paper
NM_003590.5
p.G402_L403Splc
c.1207-10A>T
4 papers
NM_003590.5
p.G402_L403Splc
c.1207-12T>G
5 papers
NM_003590.5
p.G402_L403Splc
c.1207-12T>A
1 paper
NM_003590.5
p.Q406H
c.1218A>T
1 paper
NM_003590.5
p.Q406Q
c.1218A>G
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