Varaico: Literature-Extracted Genetic Variants

Gene:CUL3
Variant:p.N39_L52del0

CUL3

494 papers

RefSeq Summary

This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core compo...

Pfam Domains

Cullinaa 34–484UCSCCullin alpha solenoid domain
Cullin_ABaa 507–665UCSCCullin alpha+beta domain
Cullin_Nedd8aa 698–760UCSCCullin protein neddylation domain

Gene Aliases

HGNC Name

cullin 3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003590.5
p.N39_L52del0
c.116_154del39
Surrounding Variants
1 paper
NM_003590.5
p.I41_G51del0
c.123_152del30
1 paper
NM_003590.5
p.L52F
c.154C>T
4 papers
NM_003590.5
p.L52V
c.154C>G
1 paper
NM_003590.5
p.G51insFs
c.153dupT
1 paper
NM_003590.5
p.S53R
c.157A>C
1 paper
NM_003590.5
p.Q42_L52del0
c.124_156del33
4 papers
NM_003590.5
p.S53N
c.158G>A
1 paper
NM_003590.5
p.S53R
c.159T>G
1 paper
NM_003590.5
p.S53R
c.159T>A
1 paper
NM_003590.5
p.G51_L52insGAA
c.151_155ins9
1 paper
NM_003590.5
p.F54L
c.160T>C
1 paper
NM_003590.5
p.F54I
c.160T>A
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