Varaico: Literature-Extracted Genetic Variants

Gene:CUL3
Variant:p.N39D

CUL3

494 papers

RefSeq Summary

This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core compo...

Pfam Domains

Cullinaa 34–484UCSCCullin alpha solenoid domain
Cullin_ABaa 507–665UCSCCullin alpha+beta domain
Cullin_Nedd8aa 698–760UCSCCullin protein neddylation domain

Gene Aliases

HGNC Name

cullin 3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003590.5
p.N39D
c.115A>G
Surrounding Variants
1 paper
NM_003590.5
p.W34_K38del0
c.101_112del12
1 paper
NM_003590.5
p.W34_N39del0
c.100_117del18
1 paper
NM_003590.5
p.L37_A40del0
c.110_118del9
1 paper
NM_003590.5
p.L37Q
c.110T>A
1 paper
NM_003590.5
p.A40A
c.120A>T
1 paper
NM_003590.5
p.L36_L37ins9
c.108_109ins27
1 paper
NM_003590.5
p.L36_L37ins4
c.108_109ins12
1 paper
NM_003590.5
p.I41N
c.122T>A
1 paper
NM_003590.5
p.L36R
c.107T>G
1 paper
NM_003590.5
p.Q42*
c.124C>T
1 paper
NM_003590.5
p.L36F
c.106C>T
1 paper
NM_003590.5
p.W34C
c.102G>T
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