Varaico: Literature-Extracted Genetic Variants

Gene:CUL4B
Variant:p.S45_S46insFs

CUL4B

149 papers

RefSeq Summary

This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell...

Pfam Domains

Cullinaa 204–646UCSCCullin alpha solenoid domain
Cullin_ABaa 668–801UCSCCullin alpha+beta domain
Cullin_Nedd8aa 832–892UCSCCullin protein neddylation domain

Gene Aliases

HGNC Name

cullin 4B

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001079872.2
p.S45_S46insFs
c.135_136insT
Surrounding Variants
1 paper
NM_001079872.2
p.S45insFs
c.134_135ins4
1 paper
NM_001079872.2
p.S45fs
c.133_134fs
1 paper
NM_001079872.2
p.S45_S46del1
c.135_137delCTG
2 papers
NM_001079872.2
p.N42delFs
c.125_126delGT
1 paper
NM_001079872.2
p.S45_S46del2
c.133_137del6
2 papers
NM_001079872.2
p.S48delFs
c.143_144delGC
1 paper
NM_001079872.2
p.N50_S51insFs
c.150_151insT
1 paper
NM_001079872.2
p.N50insFs
c.149_150ins4
1 paper
NM_001079872.2
p.K38K
c.114G>A
1 paper
NM_001079872.2
p.S49_S51del3
c.145_152del9
1 paper
NM_001079872.2
p.E54insFs
c.161dupA
1 paper
NM_001079872.2
p.R55delFs
c.163delT
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."