Varaico: Literature-Extracted Genetic Variants

CUX2

12q24.11-q24.12 (UCSC)OMIM PanelApp GTEx

171 papers

RefSeq Summary

This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is l...

Pfam Domains

CUX1_Naa 1–114UCSCCUX1-like, N-terminal tRNA-binding arm

CUTaa 549–627UCSCCUT domain

CUTaa 892–967UCSCCUT domain

CUTaa 1043–1121UCSCCUT domain

Homeodomainaa 1169–1225UCSCHomeodomain

Gene Aliases

HGNC Name

cut like homeobox 2

HGNC Previous Symbol

CUTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_015267.4

p.R129Q

c.386G>A

Surrounding Variants

1 paper

NM_015267.4

p.Q126*

c.376C>T

1 paper

NM_015267.4

p.R137T

c.410G>C

1 paper

NM_015267.4

p.E140*

c.418G>T

1 paper

NM_015267.4

p.R115S

c.345A>T

3 papers

NM_015267.4

p.A108V

c.323C>T

1 paper

NM_015267.4

p.V105A

c.314T>C

1 paper

NM_015267.4

p.P102P

c.306C>G

1 paper

NM_015267.4

p.R148G

c.442A>G

1 paper

NM_015267.4

p.T151A

c.451A>G

1 paper

NM_015267.4

p.G155R

c.463G>A

1 paper

NM_015267.4

p.G155R

c.463G>C

1 paper

NM_015267.4

p.P156S

c.466C>T