Varaico: Literature-Extracted Genetic Variants

CUX2

12q24.11-q24.12 (UCSC)OMIM PanelApp GTEx

171 papers

RefSeq Summary

This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is l...

Pfam Domains

CUX1_Naa 1–114UCSCCUX1-like, N-terminal tRNA-binding arm

CUTaa 549–627UCSCCUT domain

CUTaa 892–967UCSCCUT domain

CUTaa 1043–1121UCSCCUT domain

Homeodomainaa 1169–1225UCSCHomeodomain

Gene Aliases

HGNC Name

cut like homeobox 2

HGNC Previous Symbol

CUTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_015267.4

p.E347D

c.1041G>C

Surrounding Variants

1 paper

NM_015267.4

p.E347D

c.1041G>T

1 paper

NM_015267.4

p.E347K

c.1039G>A

4 papers

NM_015267.4

p.D337N

c.1009G>A

1 paper

NM_015267.4

p.I335I

c.1005C>T

1 paper

NM_015267.4

p.E326A

c.977A>C

1 paper

NM_015267.4

p.Q321H

c.963G>C

1 paper

NM_015267.4

p.Q321H

c.963G>T

1 paper

NM_015267.4

p.D307Y

c.919G>T

1 paper

NM_015267.4

p.Y362C

c.1085A>G

1 paper

NM_015267.4

p.A302V

c.905C>T

1 paper

NM_015267.4

p.K366I

c.1097A>T

2 papers

NM_015267.4

p.T367M

c.1100C>T