Varaico: Literature-Extracted Genetic Variants

CUX2

12q24.11-q24.12 (UCSC)OMIM PanelApp GTEx

171 papers

RefSeq Summary

This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is l...

Pfam Domains

CUX1_Naa 1–114UCSCCUX1-like, N-terminal tRNA-binding arm

CUTaa 549–627UCSCCUT domain

CUTaa 892–967UCSCCUT domain

CUTaa 1043–1121UCSCCUT domain

Homeodomainaa 1169–1225UCSCHomeodomain

Gene Aliases

HGNC Name

cut like homeobox 2

HGNC Previous Symbol

CUTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_015267.4

p.K498E

c.1492A>G

Surrounding Variants

1 paper

NM_015267.4

p.G502G

c.1506C>A

1 paper

NM_015267.4

p.L505L

c.1513C>T

1 paper

NM_015267.4

p.P509delFs

c.1526delC

1 paper

NM_015267.4

p.P508R

c.1523C>G

1 paper

NM_001370598.1

p.P447Q

c.1340C>A

NM_015267.4

p.P509Q

c.1526C>A

1 paper

NM_015267.4

p.K515fs

c.1543_1544fs

1 paper

NM_015267.4

p.P480L

c.1439C>T

1 paper

NM_015267.4

p.P516insFs

c.1546dupC

1 paper

NM_015267.4

p.T475N

c.1424C>A

2 papers

NM_015267.4

p.P454L

c.1361C>T

1 paper

NM_015267.4

p.G545G

c.1635G>C

1 paper

NM_015267.4

p.G545G

c.1635G>T