Varaico: Literature-Extracted Genetic Variants

CUX2

12q24.11-q24.12 (UCSC)OMIM PanelApp GTEx

171 papers

RefSeq Summary

This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is l...

Pfam Domains

CUX1_Naa 1–114UCSCCUX1-like, N-terminal tRNA-binding arm

CUTaa 549–627UCSCCUT domain

CUTaa 892–967UCSCCUT domain

CUTaa 1043–1121UCSCCUT domain

Homeodomainaa 1169–1225UCSCHomeodomain

Gene Aliases

HGNC Name

cut like homeobox 2

HGNC Previous Symbol

CUTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

15 papers

NM_015267.4

p.E590K

c.1768G>A

Surrounding Variants

1 paper

NM_015267.4

p.R594delFs

c.1782delG

2 papers

NM_015267.4

p.K596E

c.1786A>G

1 paper

NM_015267.4

p.H578Y

c.1732C>T

1 paper

NM_015267.4

p.V603M

c.1807G>A

1 paper

NM_015267.4

p.G572R

c.1714G>A

1 paper

NM_015267.4

p.G572R

c.1714G>C

5 papers

NM_015267.4

p.R633*

c.1897C>T

1 paper

NM_015267.4

p.G545G

c.1635G>C

1 paper

NM_015267.4

p.G545G

c.1635G>T

1 paper

NM_015267.4

p.P516insFs

c.1546dupC

1 paper

NM_015267.4

p.K515fs

c.1543_1544fs

1 paper

NM_001370598.1

p.P447Q

c.1340C>A

NM_015267.4

p.P509Q

c.1526C>A