Varaico: Literature-Extracted Genetic Variants

CUX2

12q24.11-q24.12 (UCSC)OMIM PanelApp GTEx

171 papers

RefSeq Summary

This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is l...

Pfam Domains

CUX1_Naa 1–114UCSCCUX1-like, N-terminal tRNA-binding arm

CUTaa 549–627UCSCCUT domain

CUTaa 892–967UCSCCUT domain

CUTaa 1043–1121UCSCCUT domain

Homeodomainaa 1169–1225UCSCHomeodomain

Gene Aliases

HGNC Name

cut like homeobox 2

HGNC Previous Symbol

CUTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_015267.4

p.D1234N

c.3700G>A

Surrounding Variants

1 paper

NM_015267.4

p.P1240L

c.3719C>T

2 papers

NM_015267.4

p.R1224H

c.3671G>A

1 paper

NM_015267.4

p.P1244P

c.3732T>C

1 paper

NM_015267.4

p.R1222W

c.3664C>T

1 paper

NM_015267.4

p.P1248L

c.3743C>T

1 paper

NM_015267.4

p.H1253delFs

c.3758delA

4 papers

NM_015267.4

p.H1253P

c.3758A>C

1 paper

NM_015267.4

p.D1255delFs

c.3763_3764delGA

1 paper

NM_015267.4

p.P1254_D1255del1

c.3762_3764delAGA

1 paper

NM_015267.4

p.D1255del1

c.3763_3764delGAC

1 paper

NM_015267.4

p.T1257delFs

c.3769delA

1 paper

NM_015267.4

p.T1257P

c.3769A>C