Varaico: Literature-Extracted Genetic Variants

CUX2

12q24.11-q24.12 (UCSC)OMIM PanelApp GTEx

171 papers

RefSeq Summary

This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is l...

Pfam Domains

CUX1_Naa 1–114UCSCCUX1-like, N-terminal tRNA-binding arm

CUTaa 549–627UCSCCUT domain

CUTaa 892–967UCSCCUT domain

CUTaa 1043–1121UCSCCUT domain

Homeodomainaa 1169–1225UCSCHomeodomain

Gene Aliases

HGNC Name

cut like homeobox 2

HGNC Previous Symbol

CUTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_015267.4

p.M1408L

c.4222A>T

Surrounding Variants

1 paper

NM_015267.4

p.M1408L

c.4222A>C

1 paper

NM_015267.4

p.M1408R

c.4223T>G

1 paper

NM_015267.4

p.S1399S

c.4197G>A

1 paper

NM_015267.4

p.L1395R

c.4184T>G

1 paper

NM_015267.4

p.R1388L

c.4163G>T

1 paper

NM_015267.4

p.S1379G

c.4135A>G

1 paper

NM_015267.4

p.A1439A

c.4317T>C

1 paper

NM_015267.4

p.P1375L

c.4124C>T

1 paper

NM_015267.4

p.A1369S

c.4105G>T

1 paper

NM_015267.4

p.P1453L

c.4358C>T

1 paper

NM_015267.4

p.R1458Q

c.4373G>A

1 paper

NM_015267.4

p.N1467K

c.4401C>A